Your Gift Doubles in Impact to Deliver Innovative Care

Q: Is this donation tax deductible?

Mayo Clinic is a 501(c)3 tax-exempt organization and your donation is tax deductible within the guidelines of U.S. law. To claim a donation as a deduction on your U.S. taxes, please keep your email donation receipt as your official record. We'll send it to you upon successful completion of your donation.

Q: How do I donate via cash or check?

If you would like to print and mail a check, please use the printable contribution form.

Q: Can I donate as a resident of Canada?

Yes. Please fill out the Canadian donation form.

Q: Can I donate as a resident of a GDPR country?

Yes. Please fill out the GDPR donation form.

Q: Can I designate my gift to a different Mayo Clinic program?

Yes. Please make your gift using this donation form and specify your preferred program in the "Other designation" field.

Mayo Clinic is a 501(c)3 tax-exempt organization, and your donation is tax deductible within the guidelines of U.S. law. Please keep your receipt as your official record. We'll email it to you upon successful completion of your donation.

Join our Summer of Hope Challenge

Mayo Clinic’s primary value to always put the needs of the patient first has led to incredible advancements in integrated care, research and education.

A generous benefactor has donated $100,000 and challenged us to raise an additional $100,000 by August 10. That means your gift now will DOUBLE in impact to support compassionate care, collaboration and discovery for more patients.

Mayo Clinic doctor caring for a patient.

If you prefer to make a gift with a Donor Advised Fund:

Frequently asked questions

Does my gift qualify for the challenge?

Gifts received before the deadline of August 10, 2026, qualify for this Gift Challenge. Gifts pledged or made prior to July 20, 2026, or to support special events, do not qualify for this challenge. The challenge sponsor’s gift is designated to the greatest needs at Mayo Clinic. All gifts made in response to this appeal will be directed to the greatest needs at Mayo Clinic unless otherwise noted on the gift documentation.

Your Gift Doubles in Impact to Deliver Innovative Care

2X Your Gift’s Impact

Join our Summer of Hope Challenge

Frequently asked questions

Does my gift qualify for the challenge?

Is this donation tax deductible?

How do I donate via cash or check?

Can I donate as a resident of Canada?

Can I donate as a resident of a GDPR country?

Can I designate my gift to a different Mayo Clinic program?