Every gift makes a difference

Q: Is this donation tax deductible?

Mayo Clinic is a 501(c)3 tax-exempt organization and your donation is tax-deductible within the guidelines of U.S. law. To claim a donation as a deduction on your U.S. taxes, please keep your email donation receipt as your official record. We'll send it to you upon successful completion of your donation.

Q: How do I donate via cash or check?

If you would like to print and mail a check, please use the printable contribution form.

Q: Can I donate as a resident of Canada?

Yes! Please fill out the Canadian donation form .

Q: Can I donate as a resident of a GDPR country?

Yes! Please fill out the GDPR donation form .

Q: Can I designate my gift to a different Mayo Clinic program?

Yes. Please make your gift using this donation form and specify your preferred program in the "Other designation" field.

The 2025 Year-End Challenge deadline has passed, but your gift can still help advance cancer research and care at Mayo Clinic. Thank you for your generosity and support!

Mayo Clinic is a 501(c)3 tax-exempt organization, and your donation is tax deductible within the guidelines of U.S. law. Please keep your receipt as your official record. We'll email it to you upon successful completion of your donation.

If you prefer to make a gift with a Donor Advised Fund:

Every gift makes a difference

Make 3X the Impact

Frequently asked questions

Is this donation tax deductible?

How do I donate via cash or check?

Can I donate as a resident of Canada?

Can I donate as a resident of a GDPR country?

Can I designate my gift to a different Mayo Clinic program?